ceesdekker Can Be Fun For Anyone
ceesdekker Can Be Fun For Anyone
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Spatial construction facilitates cooperation inside of a social Problem: empirical evidence from the bacterial Neighborhood
Our group reports bacterial mobile division and is also aiming to represent a ‘bottom up biology’ in synthetic cells which will autonomously divide. Our primary fascination lies in cell division, chromatin framework, and spatial Command.
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Deposition and atomic pressure microscopy of specific phthalocyanine polymers amongst nanofabricated electrodes
We develop place-of-care diagnostics check of neglected tropical diseases in just source-restricted configurations, dependant on Crspr/Cas9 detecting of pathogen’s DNA in overall body fluids.
Experimental stage diagram of negatively supercoiled DNA calculated by magnetic tweezers and fluorescence,
Due to the fact 2000 he moved to solitary-molecule biophysics and nanobiology, with study from DNA supercoiling research of nucleosomes and DNA maintenance proteins to DNA translocation by nanopores. Just lately his analysis has focused on researching cell division with bacteria on chip, though his supreme interest is in the course of recognizing artificial cells.
Atomic pressure microscopy reveals that vaccinia topoisomerase IB generates filaments on DNA inside a cooperative trend
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Resolving the stage dimension in condensin-driven DNA loop extrusion identifies ATP binding since the phase-creating approach
In 1993 he was appointed as Affiliate Professor at Delft University of Technological innovation. During the mid-1990s Dekker and his staff obtained good results with the invention of your electronic Qualities of carbon nanotubes, the primary one-molecule transistor as well as other nanoscience.
‘That problems the synthetic cell, as Element of the Dutch BaSyC initiative. Craig Venter seemed top-down in People times and recognized about 5 hundred genes that are minimally necessary for just a functioning cell. We wish to look bottom-up: how can we shift from a number of molecules to an entire Organic program?
2005, ceesdekker discovery of your mechanism of DNA uncoiling by topoisomerase enzymes; discovery of extensive-variety conformational variations in Mre11/DNA fix complexes; and initially force measurements over a DNA molecule in a nanopore
Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij fulfilled enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond intelligent design and style in 2005. (nl)